Non disease specific models
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Mechanistic models
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Paw oedema models on rats
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LPS-induced
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Carrageenan-induced
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Histamine-induced
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Elastase-induced
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Uric acid induced |
PAR2 agonist (SLIGRL-NH2)-induced |
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Paw oedema models on guinea pig
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Ovalbumin-induced on ovalbumin sensitized animals
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Plasma extarvasation models
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Capsaicin-induced tracheal and bronchial
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Antigen challenge-induced tracheal and bronchial
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Air-pouch models
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LPS-induced inflammation
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Zymosan-induced inflammation
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Phorbol-12 myristate-13 acetate (PMA)-induced inflammation
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Eotaxin-induced inflammation
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Uric acid-induced inflammation
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Organ bath technics
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Spontaneous trachel tone to test airway smooth muscle relaxing effect
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Constrictor mediator precontracted (contracture) tracheal preparation to test airway smooth muscle relaxing effect
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Antagonisation of constrictor mediator-induced constriction to test airway smooth muscle relaxing effect
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Electricaly field stimulated tracheal/bronchial preparation
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- Cholinergic contraction
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- NANC contraction
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- NANC relaxation
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Intracell Ca pool refill mechnism examination on isolated tracheal preparations changing Ca2+ containing and Ca2+ free medium
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“Skinned” tracheal preparation to test intracellular Ca mechanisms
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Ascaris suum antigen-induced tracheal constriction in sheep |
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Lung function measuring
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Konzett Rössler technics |
Airway resistance and compliance measuring by pletismograph technics |
Airway and tissue resistanec and compliance measuring by impedancy |
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